There is some low-quality evidence to support the use of stimulant laxatives for short-term use. It hasn’t been studied for long-term use, nor specifically in patients with IBS-C. Lactulose treatment, while highly effective, should not be used until other less risky treatments like PEG are attempted first. Nine controlled studies in over 500 patients show conclusive evidence in its positive effect for CC ( 9). It’s considered safe to use daily for up to 24 weeks. Polyethylene glycol (PEG) is also an effective treatment option for normalizing bowel frequency and stool consistency. Due to the high intake of magnesium, do not use this treatment option with impaired kidney function ( 8). One study comparing milk of magnesia to bulk-forming laxatives in 64 geriatric patients found it to be more effective at treating constipation. If psyllium doesn’t produce a response, then the next step is to try hyperosmotic laxatives, like milk of magnesia, at the lowest possible dose. Overall, for occasional and mild constipation, it’s best to start treatment with psyllium fiber ( 6, 7). Mineral oil also has insufficient data for its use in constipation and numerous reports of undesired side effects and poor tolerability. In fact, there is poor evidence supporting the use of docusate to treat constipation, with some concern over its occasional impact on liver function. In a study comparing psyllium husk and docusate sodium on 170 subjects for 2 weeks, researchers found psyllium to be superior in its ability to soften stools and produce a laxative effect ( 5). Overall, it’s best to pick soluble, non-fermenting fiber like psyllium husk, which is a low-risk, highly effective laxative option ( 4). However, it’s important to know that the fermentability of the fiber makes a difference in its ability to improve symptoms. First Try Psyllium Husk, A Natural Laxativeīulk-forming laxatives are typically the first line of therapy for those with constipation or IBS-C. Which Laxative Product is Most Effective?ĭifferent laxatives work best for different populations. While most are generally safe for short-term use, it’s important to talk to your doctor to find out which laxative is best suited for you. Many work by softening or moisturizing stool or by stimulating the digestive tract muscles. Summary: There are numerous laxatives available to help relieve constipation. They can also stimulate the intestines to secrete more water and salt, which helps soften stool.Įxamples include Glycerine and Fleets Phosphosoda. Suppositories work slightly differently than enemas by irritating the bottom of the intestine, causing it to contract. They are highly effective at improving constipation, typically within 2 to 15 minutes, but may cause intense urgency, bloating and cramping. This type of laxative mechanically stimulates the rectum to help empty the bowels.Įnemas are either water or salt solutions ( not coffee) that are pushed into the rectum via a prepared enema, enema bulb or fountain syringe.
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